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Innovative Technology Development (ITD) Program

 
   
 

ITD Program Overview

The Innovative Technology Development (ITD) Program is designed to help bridge the gap between early-stage technology discovery and development capabilities of the academic community and later-stage commercial development interests of the bioscience industry. While the program has, in the past, invested independently in commercially promising faculty research, current New York State guidelines require that ITD project investments be match-funded by a New York State company sponsor.

The ITD program currently provides matching funds to support translational research on the Stony Brook campus in all areas of medical biotechnology. These areas include research technologies, diagnostics, therapeutics and medical devices. This funding, in tandem with the broad range of technology development services available through the Center for Biotechnology, is intended to help New York Sate companies identify commercial opportunities from within the basic research enterprise on campus, add value by providing guidance and financial support for their development toward commercial goals, and accelerate technology entry into the marketplace where they can improve healthcare and further enhance biomedical research. The primary interest is in supporting discovery and development of technologies that have the potential to significantly and positively impact the New York State economy. The Program will also co-fund further development of existing New York State company intellectual property when in collaboration with Stony Brook University faculty.

Applications must clearly discuss commercial potential of the technology and potential for economic impact in New York State. Center for Biotechnology staff members are available throughout the year to assist in fostering collaborative relationships between faculty and New York State industry, and to assist in development of both technical and commercialization strategies. It is strongly encouraged that potential applicants seek guidance from the Center prior to submission of an application.

Technology Development Pipeline

The Center for Biotechnology’s technology development pipeline represents approximately twenty biomedical projects at various stages of development. Financial investments do not support basic research, but rather focus on translation of basic research discoveries into commercially viable technologies. Investments share risk with company partners, and while modest, add significant value at an early stage, particularly when coupled with commercial development guidance of the Center’s staff. Technologies developed with Center support include;

Genetic System to Detect Protein-Protein Interactions
Stanley Fields, Ph.D., inventor
Licensed to more than 45 companies worldwide

Antisense Technology
Masayori Inouye, Ph.D., inventor
Licensed to Enzo Biochem, Inc.

Biomaterial Applications of Hyaluronic Acid
Glenn Prestwich, Ph.D., inventor
Technical basis for the formation of Clear Solutions Biotech, Inc.

Low Level Biomedical Prophylaxis for the Inhibition of Osteopenia
Clinton Rubin, Ph.D., Kenneth McLeod, Ph.D., inventors
Technical basis for the formation of Exogen, now with Smith & Nephew

3-D Virtual Colonoscopy
Arie Kaufman, Ph.D., Jerome Liang, Ph.D., inventors
Technical basis for the formation of Viatronix, Inc.

Bioabsorbable Membranes
Benjamin Hsiao, Ph.D., Benjamin Chu, Ph.D., inventors
Technical basis for formation of Stony Brook Technology & Applied Research, Inc.

Scanning Confocal Ultrasonic Diagnostic System for Bone Quality
Yi-Xian Qin, Ph.D., Clinton Rubin, Ph.D., inventors
Technical basis for the formation of AcousticScan, Inc.

Development of a Technology to Identify Anti-Metastatic Drugs
Wen-Tien Chen, Ph.D., inventor
Technical basis for the formation of Vitatex, Inc.

A Novel, Cancer Chemotherapeutic Agent
Paul Bingham, Ph.D., inventor
Technical basis for the formation of Cornerstone Pharmaceuticals, Inc.

Summary of Program Objectives

  • Stimulate and accelerate discovery and development of commercially promising technologies within the academic environment and in partnership with NYS bioscience companies.
  • Work collaboratively with faculty and NYS bioscience companies to develop commercially significant experimental protocols that will add value to intellectual property with potential to generate economic impact in New York State.
  • Assist in moving these technologies down a commercial pathway by participating in development of critical path management strategies, facilitating financing opportunities, facilitating out-licensing, and identifying potential commercial partners.

Past ITD Awards

Program Guidelines

The Center for Biotechnology will provide match-funding of $50K for new translational research projects proposed in collaboration with NYS corporate partners.  New York State corporate partners are required to provide a 1: 1 match (years 1 and 2) for a total project award of $100K per year.  Proposals for the third year of funding require a 2:1 match from the corporate partner.  Larger awards are available based upon project needs but should be discussed prior to application and are subject to the discretion of the ITD Advisory Board.  Multi-year (up to 3 years) awards will be available starting with the 2008 ITD Program and will be subject to annual renewals based upon performance.  All funds must be used to support research and development activities on the academic campus.  Awards cannot be used to fund research activities at the corporate sponsor's location.  Project evaluation is based upon quality of the science, degree of commitment from the corporate sponsor, commercial opportunity, and potential for economic impact in NYS.  Projects that demonstrate the potential to generate economic/commercial impact (licensing revenue, SBIR/STTR funding, expanded corporate investment, new jobs, etc.) in the short-term (1-5 years) are a priority, although this is not a requirement.  A letter of support from the company detailing their financial commitment to the project must accompany the application.  Funding is not intended to subsidize current, ongoing research projects between the PI and company, but rather to stimulate new areas of investigation that would not otherwise move forward.  The goal is to reduce risk to the corporate partner associated with exploring new areas of investigation, while cultivating new sources of funding for the PI. 

All New York State-sponsored research projects conducted in partnership with the Center for Biotechnology qualify for a reduced indirect cost rate of 15%, a savings of 40% over the University’s published corporate rate.  A research contract will be implemented by the SUNY Research Foundation if the project is approved for funding.  A template/generic copy of the Research Foundation’s corporate sponsored research contract is available for review although specific details of each project will be addressed in a customized contract if the project is selected for funding.  Proposals for a second or third year of funding require a progress report, new application, and new letter of support from the corporate sponsor.  Proposals for a third year of funding require a minimum 2:1 match from the corporate partner.  All potential applicants are strongly encouraged to contact and meet with Michael R. Bielski, J.D., M.S., Assistant Director, Science & Technology Commercialization prior to submission.
 

Application Guidelines

Submission of Proposals
ITD Application instructions/forms can be downloaded from the Center's web site or can be requested by telephone at 631-632-8521. One original hardcopy and one electronic copy (CD) of the proposal, together with one copy of form SUSB 299 (4-page signature form from Sponsored Programs) with approval from the Office of Sponsored Programs should be submitted to:

The Center for Biotechnology, ITD Program
Psychology A Building, 3rd Floor
Stony Brook University
Stony Brook, NY 11794-2580

The deadline for receipt of proposals is 4pm Friday, Feb 1, 2008. Applications are accepted and considered on a competitive basis and subject to the availability of funds.  

Budget Restrictions
ITD projects run from July 1st through June 15th of each year (contract period is July 1st – June 30th). Unexpended funds as of June 15th cannot be carried over from one fiscal year to the next. Funding is available for salaries of postdoctoral fellows, technicians and other non-faculty project personnel, supplies, equipment, and miscellaneous expenses. Research Faculty who are PI’s or Co-PI’s can allocate up to $6,000 for salary support. Award funds cannot be used for faculty salaries (tenure or tenure-track), building renovations, travel, meetings, entertainment, consultants, computers (unless directly related to project), or office equipment. Equipment purchases over $5,000 must be dedicated to the project and have prior Center approval. The budget request should include the current appropriate fringe benefit rate(s) for non-faculty/technical personnel or graduate students, as established by the Research Foundation of SUNY. If graduate students will be working on the project please include tuition reimbursement as required by the Stony Brook University Graduate School. For fiscal year 2007-08 graduate student tuition is $1725 per semester, or $3450 per year, and should be prorated based on percentage effort. Discounted indirect costs (IDC; 15% versus current campus rate of 55%) are included on both the company and Center budgets. The Center budget includes 15% indirect costs of total personnel only. The company budget includes 15% indirect costs of total direct costs. "In-kind" (non-cash) contributions from a company require prior approval from the Center and will be considered on a case-by-case basis. If approved, "In-kind" contributions should be labeled “in-kind” on the company budget form.

Proposal Evaluation
Proposals will be evaluated by Center staff and an external ITD Advisory Panel.  Advisory panel members are selected from the academic, business, and investment communities.  All members sign a confidentiality agreement to protect confidential information provided in the application.  Applications must support research that has significant potential for economic impact in NYS.  Project evaluation is based upon quality of the science, commercial potential, commitment of the sponsor, and level of economic impact in NYS.  Projects that demonstrate potential to generate economic impact in the near term (1-5 years) are prioritized.  Economic impact can include expanded corporate funding for the technology, SBIR/STTR funding, licensing, corporate savings, or new job creation at the corporate partner’s location related to ongoing project development, etc.  All corporate partners that participate in the ITD program are required to document economic impact of the program in writing on an annual basis at the Center’s request.

Award Administration
The PI is responsible for administering award funds and ensuring that overdrafts do not occur.  Unexpended funds cannot be carried over to a new fiscal year.  The funding period is July 1 - June 15 of each year, or any portion there of.  Twice a year the Center for Biotechnology is required to report to its own sponsor, NYSTAR, on aggregate corporate research expenditures related to the entire ITD program.  Therefore, acceptance of funding by the PI will include authorization of a Center employee to be listed on the RF award as an “authorized viewer”.  Equipment purchased with ITD funds is the property of The Research Foundation of SUNY.  In exceptional cases, it may be possible to split funding between two different fiscal years.  However, all changes require prior approval by the Center and will be considered on a case by case basis.

Reporting Requirements
The PI must submit a non-proprietary 6-month progress report (one page maximum) by Jan 15th and a one page final progress report by July 15th.   These should be sent electronically to mbielski@stonybrook.edu.  Twice a year, the Center is required to report on aggregate corporate research expenditures related to the ITD program.  To facilitate collection of this information, acceptance of ITD funding by the PI authorizes Center staff to periodically review corporate accounts related to ITD awards.  The Center’s sponsor, NYSTAR, also requires all companies that participate in Center programs to document in writing, on an annual basis, the economic impact of Center funding.  A letter on company letterhead from a senior company official describing jobs created/retained by the company partner and estimates of other economic impact is sufficient.  The Center will solicit these letters on an annual basis.  All publications, patents and communications resulting from Center support should acknowledge “the Center for Biotechnology, a New York State Center for Advanced Technology,” as well as company support.
 

2008 ITD Downloads

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